In view of the reduction of sound insulation performance due to the lightweight design of railway vehicles, the effect of different stiffener sections on the sound insulation enhancement is studied. The prediction model of sound insulation characteristics of stiffened plate for railway vehicles was built based on the hybrid method of finite element and statistical energy analysis (Hybrid FE-SEA), and the effects of stiffener sections on the sound insulation characteristics of the plate were systematically analyzed. The section types include T-type, L-type, I-type and rectangular type. The results show that the stiffness and the first natural frequency of the stiffened plate are larger than that of the homogeneous plate, and increase with the increase of stiffener thickness. When the stiffener thickness is constant, the stiffness and the first natural frequency of the T stiffened plate are the largest, and the L stiffened plate is second. Laying thickness of 15mm stiffener, the sound insulation performance of plate is the best. When the mass, thickness, web area and size, wing area of the stiffeners are equal, there is little difference in the weighted sound transmission loss of various types of stiffened plates. In addition, after the panel is reinforced, the sound insulation at the stiffness control zone is increased by 3~17 dB, and the sound insulation between 1250~4000 Hz frequency bands is increased by 1~6 dB. Comprehensive analysis indicates that taking weighted sound insulation is used as the evaluation standard, the thickness of stiffener is 15mm when the stiffener mass, web area, wing area and size are equal, and the sound insulation performance of the plate is the best, Rw is 1.4~1.5 dB higher than that of the homogeneous plate, and the stiffness of T-type and L-type stiffened plates is the best when the stiffener thickness is constant. The related research results can provide reinforced optimization design reference for plate of railway vehicles.