Aimed at the disadvantages of traditional fracturing pumps, such as high frequency of stroke, the short lifetime of easy wear parts, and so on, the hydraulic driven fracturing pump was proposed. And the half-open and half-closed circuit hydraulic system was designed. The simulation model and test prototype were built. The results showed that the model was accurate. And the high pressure also can be achieved by the hydraulic driven fracturing pump. Because of the leakage of hydraulic cylinders, Westphal Phenomena and the natural switch time of system, pressure and flow pulsation were existed, and increased with the increase of load pressure. According to the characteristics of pressure and flow pulsation, the pulse suppression device was designed, which was consisted of the piston cylinder, pneumatic cylinder and accumulator group. The results showed that the pulsation was significantly suppressed by this device, and decreased with the increase of the volume or pre-charge pressure of accumulator. With the help of this device, the pulsation of hydraulic driven fracturing pump with three-cylinder equal to the traditional fracturing pump with five-cylinder.