ccording to domestic natural gas as fuel for gas - steam combined-cycle thermal power plant characteristic, it was known that the steam turbine engine, gas turbine, waste heat boiler, mechanical ventilation cooling tower, transformer, natural gas and other areas, as well as the circulating water pump room, water plant and other auxiliary equipment room are the main noise radiation zone. The analysis on these region acoustic source equipment and the acoustic source characteristic was carried out simultaneously. Specific control measures to the key source of regional noise were put forward